Crestline Partners
“Scale your science, without the overhead.”
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About Us
Mission
Empower mid-sized biotech innovators with the same caliber of strategy, analytics, and execution usually reserved for Fortune 500 enterprises—delivered faster, leaner, and at a cost that protects your R&D runway.
Why We're Different
• Enterprise-grade know-how, boutique speed. Seasoned consultants who have led global biotech transformations—now working in focused, two- to four-person squads that move at the pace your science demands.• 90-day sprint model. Up-front assessment → prioritized roadmap → execution sprint, so value starts showing in a single quarter, not after a year of slide decks.• No cookie-cutter playbooks. Every engagement is built around the KPIs that matter to you—whether that’s first-patient-in dates, COGS per batch, or audit-readiness scores.• Cost transparency. Fixed-fee packages and milestone-based billing keep incentives aligned and surprises off the table.
Service Offerings
| Service Offering | Typical Duration | Goals | Your Deliverables |
|---|---|---|---|
| Diagnostic Assessment | 3-4 weeks (fixed scope) | Expose critical process & tech gaps and hand you an ROI-ranked roadmap | • On-site workshops • Maturity scorecard |
| Acceleration Sprint | ~12 weeks, agile workstreams | Implement the top 3 fixes and show hard ROI by week 12 | • Project charter • Weekly stand-ups |
| Fractional Advisory | Month-to-month | Act as your on-call Advisor —steering vendors, tracking OKRs, and prepping board-ready insights. | • Monthly OKR review & risk log • Board-deck slide pack each quarter |
Proven Impact
• Operational‑model redesign of a $23 M digital‑transformation program, collaborating with multiple VPs and stakeholders to save $15 M in Safety and $9 M in Commercial Analytics
• Drove M&A due diligence and integration by facilitating workshops with directors and executives, identifying synergies that created $10 M+ in cost savings and operational efficiencies
• ↑ 40 % patient engagement for a top‑5 biopharma by deploying an AI‑driven registry and smart‑recruitment portal
• 60+ legacy clinical systems integrated into a centralized virtual CTMS for a global pharma, streamlining data access and inspection readiness.
• Managed‑services program cut vendor spend 20 % and secured a $10 M multi‑year contract for a leading biotech
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